abstract：:The phase-response curve (PRC), relating the phase shift of an oscillator to external perturbation, is an important tool to study neurons and their population behavior. It can be experimentally estimated by measuring the phase changes caused by probe stimuli. These stimuli, usually short pulses or continuous noise, ha...

journal_title：Journal of neurophysiology

authors： Hong S,Robberechts Q,De Schutter E

更新日期：2012-10-01 00:00:00

abstract：:Distinguishing which of the many proposed neural mechanisms of spatial attention actually underlies behavioral improvements in visually guided tasks has been difficult. One attractive hypothesis is that attention allows downstream neural circuits to selectively integrate responses from the most informative sensory neu...

journal_title：Journal of neurophysiology

authors： Masse NY,Herrington TM,Cook EP

更新日期：2012-09-01 00:00:00

abstract：:The mechanisms and impact of correlated, or synchronous, firing among pairs and groups of neurons are under intense investigation throughout the nervous system. A ubiquitous circuit feature that can give rise to such correlations consists of overlapping, or common, inputs to pairs and populations of cells, leading to ...

journal_title：Journal of neurophysiology

authors： Barreiro AK,Thilo EL,Shea-Brown E

更新日期：2012-09-01 00:00:00

abstract：:Microelectrode arrays (MEAs) are appealing tools to probe large neural ensembles and build neural prostheses. Microelectronics microfabrication technologies now allow building high-density MEAs containing several hundreds of microelectrodes. However, several major problems become limiting factors when the size of the ...

journal_title：Journal of neurophysiology

authors： Heim M,Rousseau L,Reculusa S,Urbanova V,Mazzocco C,Joucla S,Bouffier L,Vytras K,Bartlett P,Kuhn A,Yvert B

更新日期：2012-09-01 00:00:00

abstract：:Attention is thought to improve most aspects of perception. However, we recently showed that, somewhat surprisingly, endogenous attention can also lead to low subjective perceptual ratings (Rahnev et al., 2011). Here we investigated the neural basis of this effect and tested whether spontaneous fluctuations of the att...

journal_title：Journal of neurophysiology

authors： Rahnev DA,Bahdo L,de Lange FP,Lau H

更新日期：2012-09-01 00:00:00

abstract：:Previous research has described kinetic characteristics of treadmill steps in very stable steppers, in cross-sectional designs. In this study we examined, longitudinally, muscle activation patterns during treadmill stepping, without practice, in 12 healthy infants at 1, 6, and 12 mo of age. We assessed lateral gastroc...

journal_title：Journal of neurophysiology

authors： Teulier C,Sansom JK,Muraszko K,Ulrich BD

更新日期：2012-08-01 00:00:00

abstract：:Pain signals threat and initiates motor responses to avoid harm. The transformation of pain into a motor response is thus an essential part of pain. Here, we investigated the neural mechanisms subserving the sensorimotor transformation of pain at the cortical level by using electroencephalography. In a simple reaction...

journal_title：Journal of neurophysiology

authors： Schulz E,Tiemann L,Witkovsky V,Schmidt P,Ploner M

更新日期：2012-08-01 00:00:00

abstract：:Two identified locust neurons, the lobula giant movement detector (LGMD) and its postsynaptic partner, the descending contralateral movement detector (DCMD), constitute one motion-sensitive pathway in the visual system that responds preferentially to objects that approach on a direct collision course and are implicate...

journal_title：Journal of neurophysiology

authors： McMillan GA,Gray JR

更新日期：2012-08-01 00:00:00

abstract：:Several studies have demonstrated that motor adaptations to a novel task environment can be transferred between limbs. Such interlimb transfer of motor commands is consistent with the notion of centrally driven strategies that can be generalized across different frames of reference. So far, studies of interlimb transf...

journal_title：Journal of neurophysiology

authors： Houldin A,Chua R,Carpenter MG,Lam T

更新日期：2012-08-01 00:00:00

abstract：:Motor networks such as the pyloric network of the stomatogastric ganglion often require descending neuromodulatory inputs to initiate, regulate, and modulate their activity and their synaptic connectivity to manifest physiologically appropriate output. Prolonged removal of these descending inputs often results in a co...

journal_title：Journal of neurophysiology

authors： Nahar J,Lett KM,Schulz DJ

更新日期：2012-08-01 00:00:00

abstract：:Vision in natural situations is different from the paradigms generally used to study vision in the laboratory. In natural vision, stimuli usually appear in a receptive field as the result of saccadic eye movements rather than suddenly flashing into view. The stimuli themselves are rich with meaningful and recognizable...

journal_title：Journal of neurophysiology

authors： Ruiz O,Paradiso MA

更新日期：2012-07-01 00:00:00

abstract：:When linking in time electrical stimulation of the peripheral nerve with transcranial magnetic stimulation (TMS), the excitability of the motor cortex can be modulated to evoke clear inhibition, as reflected by the amplitude decrement in the motor-evoked potentials (MEPs). This specific property, designated short-late...

journal_title：Journal of neurophysiology

authors： Ferreri F,Ponzo D,Hukkanen T,Mervaala E,Könönen M,Pasqualetti P,Vecchio F,Rossini PM,Määttä S

更新日期：2012-07-01 00:00:00

abstract：:Odor identification (OI) tests are increasingly used clinically as biomarkers for Alzheimer's disease and schizophrenia. The aim of this study was to directly compare the neuronal correlates to identified odors vs. nonidentified odors. Seventeen females with normal olfactory function underwent a functional magnetic re...

journal_title：Journal of neurophysiology

authors： Kjelvik G,Evensmoen HR,Brezova V,Håberg AK

更新日期：2012-07-01 00:00:00

abstract：:A description of healthy and pathological brain dynamics requires an understanding of spatiotemporal patterns of neural activity and characteristics of its propagation between interconnected circuits. However, the structure and modulation of the neural activation maps underlying these patterns and their propagation re...

journal_title：Journal of neurophysiology

authors： Hazra A,Rosenbaum R,Bodmann B,Cao S,Josić K,Žiburkus J

更新日期：2012-07-01 00:00:00

abstract：:The rapid detection of sensory inputs is crucial for survival. Sensory detection explicitly requires the integration of incoming sensory information and the ability to distinguish between relevant information and ongoing neural activity. In this study, head-fixed rats were trained to detect the presence of a brief def...

journal_title：Journal of neurophysiology

authors： Ollerenshaw DR,Bari BA,Millard DC,Orr LE,Wang Q,Stanley GB

更新日期：2012-07-01 00:00:00

abstract：:The axons that project into the striatum are known to segregate according to macroscopic cortical systems; however, the within-region organization of these fibers has yet to be described in humans. We used in vivo fiber tractography, in neurologically healthy adults, to map white matter bundles that originate in diffe...

journal_title：Journal of neurophysiology

authors： Verstynen TD,Badre D,Jarbo K,Schneider W

更新日期：2012-06-01 00:00:00

abstract：:Early visual motion signals are local and one-dimensional (1-D). For specification of global two-dimensional (2-D) motion vectors, the visual system should appropriately integrate these signals across orientation and space. Previous neurophysiological studies have suggested that this integration process consists of tw...

journal_title：Journal of neurophysiology

authors： Amano K,Takeda T,Haji T,Terao M,Maruya K,Matsumoto K,Murakami I,Nishida S

更新日期：2012-06-01 00:00:00

abstract：:Motoneurons receive synaptic inputs from tens of thousands of connections that cause membrane potential to fluctuate continuously (synaptic noise), which introduces variability in discharge times of action potentials. We hypothesized that the influence of synaptic noise on force steadiness during voluntary contraction...

journal_title：Journal of neurophysiology

authors： Dideriksen JL,Negro F,Enoka RM,Farina D

更新日期：2012-06-01 00:00:00

abstract：:In quadrupeds, the dorsal-side-up body orientation during standing is maintained due to a postural system that is driven by feedback signals coming mainly from limb mechanoreceptors. In caudally decerebrated (postmammillary) rabbits, the efficacy of this system is considerably reduced. In this paper, we report that th...

journal_title：Journal of neurophysiology

authors： Zelenin PV,Hsu LJ,Orlovsky GN,Deliagina TG

更新日期：2012-06-01 00:00:00

abstract：:Synaptic interactions between nearby excitatory and inhibitory neurons in the neocortex are thought to play fundamental roles in sensory processing. Here, we have combined optogenetic stimulation, whole cell recordings, and computational modeling to define key functional microcircuits within layer 2/3 of mouse primary...

journal_title：Journal of neurophysiology

authors： Avermann M,Tomm C,Mateo C,Gerstner W,Petersen CC

更新日期：2012-06-01 00:00:00

abstract：:Mechanoelectric transducer (MET) channels, located near stereocilia tips, are opened by deflecting the hair bundle of sensory hair cells. Defects in this process result in deafness. Despite this critical function, the molecular identity of MET channels remains a mystery. Inherent channel properties, particularly those...

journal_title：Journal of neurophysiology

authors： Pan B,Waguespack J,Schnee ME,LeBlanc C,Ricci AJ

更新日期：2012-05-01 00:00:00

abstract：:Although previous research with human and nonhuman primates has examined the neural correlates of performance monitoring, discrepancies in methodology have limited our ability to make cross-species generalizations. One major obstacle arises from the use of different behavioral responses and tasks across different prim...

journal_title：Journal of neurophysiology

authors： Reinhart RM,Carlisle NB,Kang MS,Woodman GF

更新日期：2012-05-01 00:00:00

abstract：:The widespread noradrenergic innervation in the brain promotes arousal and learning by molecular mechanisms that remain largely undefined. Recent work shows that the β(2)-adrenergic receptor (β(2)AR) is linked to the AMPA-type glutamate receptor subunit GluA1 via stargazin and PSD-95 (Joiner ML, Lise MF, Yuen EY, Kam ...

journal_title：Journal of neurophysiology

authors： Qian H,Matt L,Zhang M,Nguyen M,Patriarchi T,Koval OM,Anderson ME,He K,Lee HK,Hell JW

更新日期：2012-05-01 00:00:00

abstract：:A major goal of neuroscience is to understand the functions of networks of neurons in cognition and behavior. Recent work has focused on implanting arrays of ∼100 immovable electrodes or smaller numbers of individually adjustable electrodes, designed to target a few cortical areas. We have developed a recording system...

journal_title：Journal of neurophysiology

authors： Feingold J,Desrochers TM,Fujii N,Harlan R,Tierney PL,Shimazu H,Amemori K,Graybiel AM

更新日期：2012-04-01 00:00:00

abstract：:Previous studies using advanced matrix factorization techniques have shown that the coordination of human voluntary limb movements may be accomplished using combinations of a small number of intermuscular coordination patterns, or muscle synergies. However, the potential use of muscle synergies for isometric force gen...

journal_title：Journal of neurophysiology

authors： Roh J,Rymer WZ,Beer RF

更新日期：2012-04-01 00:00:00

abstract：:Hierarchical models of auditory processing often posit that optimal stimuli, i.e., those eliciting a maximal neural response, will increase in bandwidth and decrease in modulation rate as one ascends the auditory neuraxis. Here, we tested how bandwidth and modulation rate interact at several loci along the human centr...

journal_title：Journal of neurophysiology

authors： Overath T,Zhang Y,Sanes DH,Poeppel D

更新日期：2012-04-01 00:00:00

abstract：:To investigate how hippocampal neurons encode sound stimuli, and the conjunction of sound stimuli with the animal's position in space, we recorded from neurons in the CA1 region of hippocampus in rats while they performed a sound discrimination task. Four different sounds were used, two associated with water reward on...

journal_title：Journal of neurophysiology

authors： Itskov PM,Vinnik E,Honey C,Schnupp J,Diamond ME

更新日期：2012-04-01 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) can produce a lasting polarity-specific modulation of cortical excitability in the brain, and it is increasingly used in experimental and clinical settings. Recent studies suggest that the after-effects of tDCS are related to molecular mechanisms of activity-dependent syn...

journal_title：Journal of neurophysiology

authors： Ranieri F,Podda MV,Riccardi E,Frisullo G,Dileone M,Profice P,Pilato F,Di Lazzaro V,Grassi C

更新日期：2012-04-01 00:00:00

abstract：:The medial-olivocochlear (MOC) acoustic reflex is thought to provide frequency-specific feedback that adjusts the gain of cochlear amplification, but little is known about how frequency specific the reflex actually is. We measured human MOC tuning through changes in stimulus frequency otoacoustic emissions (SFOAEs) fr...

journal_title：Journal of neurophysiology

authors： Lilaonitkul W,Guinan JJ Jr

更新日期：2012-03-01 00:00:00

abstract：:Damage to the cerebellum causes characteristic movement abnormalities but is thought to have minimal impact on somatosensory perception. Traditional clinical assessments of patients with cerebellar lesions reveal no perceptual deficits despite the fact that the cerebellum receives substantial somatosensory information...

journal_title：Journal of neurophysiology

authors： Bhanpuri NH,Okamura AM,Bastian AJ

更新日期：2012-03-01 00:00:00

abstract：:Ifenprodil is a selective blocker of NMDA receptors that are heterodimers composed of GluN1/GluN2B subunits. This pharmacological profile has been extensively used to test the role of GluN2B-containing NMDA receptors in learning and memory formation. However, ifenprodil has also been reported to have actions at a numb...

journal_title：Journal of neurophysiology

authors： Delaney AJ,Power JM,Sah P

更新日期：2012-03-01 00:00:00

abstract：:Attention is known to affect the response properties of sensory neurons in visual cortex. These effects have been traditionally classified into two categories: 1) changes in the gain (overall amplitude) of the response; and 2) changes in the tuning (selectivity) of the response. We performed an extensive series of beh...

journal_title：Journal of neurophysiology

authors： Paltoglou AE,Neri P

更新日期：2012-03-01 00:00:00

abstract：:Adaptation of movement may be driven by the difference between planned and actual motor performance, or the difference between expected and actual sensory consequences of movement. To identify how the nervous system differentially uses these signals, we asked: does motor adaptation occur when movement errors are irrel...

journal_title：Journal of neurophysiology

authors： Schaefer SY,Shelly IL,Thoroughman KA

更新日期：2012-02-01 00:00:00

abstract：:Training rats to perform rapidly and efficiently in an olfactory discrimination task results in robust enhancement of excitatory and inhibitory synaptic connectivity in the rat piriform cortex, which is maintained for days after training. To explore the mechanisms by which such synaptic enhancement occurs, we recorded...

journal_title：Journal of neurophysiology

authors： Saar D,Reuveni I,Barkai E

更新日期：2012-02-01 00:00:00

abstract：:Noise is a major concern in circuits processing electrical signals, including neural circuits. There are many factors that influence how noise propagates through neural circuits, and there are few systems in which noise levels have been studied throughout a processing pathway. We recorded intracellularly from multiple...

journal_title：Journal of neurophysiology

authors： Jones PW,Gabbiani F

更新日期：2012-02-01 00:00:00

abstract：:Electrical stimulation of the median nerve at the wrist may elicit a blink reflex [hand blink reflex (HBR)] mediated by a neural circuit at brain stem level. As, in a Sherringtonian sense, the blink reflex is a defensive response, in a series of experiments we tested, in healthy volunteers, whether and how the HBR is ...

journal_title：Journal of neurophysiology

authors： Sambo CF,Liang M,Cruccu G,Iannetti GD

更新日期：2012-02-01 00:00:00

abstract：:We have addressed the source and nature of the persistent neural activity that bridges the stimulus-free gap between the conditioned stimulus (CS) and unconditioned stimulus (US) during trace eyelid conditioning. Previous work has demonstrated that this persistent activity is necessary for trace eyelid conditioning: C...

journal_title：Journal of neurophysiology

authors： Siegel JJ,Kalmbach B,Chitwood RA,Mauk MD

更新日期：2012-01-01 00:00:00

abstract：:ACh modulates neuronal activity throughout the cerebral cortex, including the primary visual cortex (V1). However, a number of issues regarding this modulation remain unknown, such as the effect and its function and the receptor subtypes involved. To address these issues, we combined extracellular single-unit recordin...

journal_title：Journal of neurophysiology

authors： Soma S,Shimegi S,Osaki H,Sato H

更新日期：2012-01-01 00:00:00

abstract：:Expression of the 5-HT(1Apl(a)) receptor in Aplysia pleural sensory neurons inhibited 5-HT-mediated translocation of the novel PKC Apl II in sensory neurons and prevented PKC-dependent synaptic facilitation at sensory to motoneuron synapses (Nagakura et al. 2010). We now demonstrate that the ability of inhibitory rece...

journal_title：Journal of neurophysiology

authors： Dunn TW,Farah CA,Sossin WS

更新日期：2012-01-01 00:00:00

abstract：:Reaching movements are subject to noise associated with planning and execution, but precisely how these noise sources interact to determine patterns of endpoint variability in three-dimensional space is not well understood. For frontal plane movements, variability is largest along the depth axis (the axis along which ...

journal_title：Journal of neurophysiology

authors： Apker GA,Buneo CA

更新日期：2012-01-01 00:00:00